轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)活性蛋白
Active Transforming Growth Factor Beta 1 (TGFb1)
TGF-B1; CED; DPD1; LAP; Camurati-Engelmann Disease; Latency-associated peptide
- 編號(hào)UAPA124Hu63
- 物種Homo sapiens (Human，人) 相同的名稱，不同的物種。
- 緩沖液成份PBS, pH7.4, containing 5% Trehalose.
- 性狀凍干粉
- 純度> 80%
- 等電點(diǎn)8.4
- 應(yīng)用Cell?culture;?Activity?Assays.
- 下載 英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格 10μg50μg 200μg 1mg 5mg
- 價(jià)格 ¥ 696 ¥ 1740 ¥ 3480 ¥ 10440 ¥ 26100
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產(chǎn)品包裝(模擬)
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產(chǎn)品包裝(模擬)
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Figure. SDS-PAGE
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通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
活性實(shí)驗(yàn)
Transforming Growth Factor Beta 1 (TGFB1) belongs to TGF-beta family. As a secreted protein and a cytokine, TGFB plays a role in the formation of blood vessels, the regulation of muscle tissue and body fat development, wound healing, and immune system function. Besides, TGFB1 regulates cell proliferation, differentiation, adhesion, migration by transducing the signal through transmembrane receptors type I and type II (TGFBR1 and TGFBR2). To test the effect of TGFb1 on inhibit IL4-dependent proliferation, CTLL-2 cells were seeded into triplicate wells of 96-well plates, the medium was 2% serum RPMI-1640?including various concentrations of recombinant human TGFb1. After incubated for 72h,?cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10 μl of CCK-8 solution was added to each well of the plate, then the absorbance at 450 nm was measured. Cell viability was assessed by CCK-8 assay. The result was shown in Figure1. It was obvious that TGFB1 significantly decreased cell viability of CTLL-2 cells. The ED50 of recombinant human TGFB1 is 2.91μg/mL.
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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| 編號(hào) | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| URPA124Hu02 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPA124Hu64 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPA124Hu63 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPA124Hu65 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| URPA124Hu01 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UAPA124Hu63 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)活性蛋白 | Cell?culture;?Activity?Assays. |
| UAPA124Hu01 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)活性蛋白 | Cell?culture;?Activity?Assays. |
| UEPA124Hu62 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UEPA124Hu61 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)真核蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| UPAA124Hu01 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)多克隆抗體 | IHC |
| ULAA124Hu71 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| ULAA124Hu81 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)多克隆抗體(異硫氰酸熒光素標(biāo)記) | WB; IHC; ICC; IF. |
| UMAA124Hu23 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 | IHC |
| UMAA124Hu24 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 | IHC |
| UMAA124Hu25 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 | WB; IHC |
| URAA124Hu21 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)重組抗體 | WB; IF; ICC; IHC; IP; FCM. |
| UMAA124Hu27 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 | WB |
| UMAA124Hu29 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 | ICC/IF |
| UMAA124Hu21 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 | IHC |
| UMAA124Hu26 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 | ICC/IF |
| UMAA124Hu28 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 | ICC/IF |
| UMAA124Hu22 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 | WB |
| UFAA124Hu02 | 抗轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體 | FCM |
| ULAA124Hu82 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體(異硫氰酸熒光素標(biāo)記) | WB; IHC; ICC; IF. |
| ULAA124Hu72 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)單克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| UMEA124Hu | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法,小樣本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| USEA124Hu | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| USCA124Hu | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)檢測(cè)試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| ULMA124Hu | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
| UPSA124Hu01 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)抗體對(duì) | ELISA; CLIA; ELISPOT; Luminex; Immunochromatography and other Immunoassays. |
| UKSA124Hu01 | 轉(zhuǎn)化生長(zhǎng)因子β1(TGFb1)檢測(cè)試劑盒DIY材料(酶聯(lián)免疫吸附試驗(yàn)法) | Main materials for "Do It (ELISA Kit) Yourself". |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Cardiovascular Research | Metformin attenuates cardiac fibrosis by inhibiting the TGFβ1–Smad3 signalling pathway [OxfordJournals: source] |
| Immunopharmacology and Inflammation | Evidence for the complementary and synergistic effects of the three-alkaloid combination regimen containing berberine, hypaconitine and skimmianine on the ulcerative colitis rats induced by trinitrobenzene-sulfonic acid [ScienceDirect: S0188440910001049] |
| Biochemical and Biophysical Research Communications | Chronic angiotensin-(1–7) administration improves vascular remodeling after angioplasty through the regulation of the TGF-β/Smad signaling pathway in rabbits [ScienceDirect: S0006291X09017021] |
| European Cells and Materials | Incorporating pTGF-β1/calcium phosphate nanoparticles with fibronectin into 3-dimensional collagen/chitosan scaffolds: efficient, sustained gene delivery to stem cells for chondrogenic differentiation. [Pubmed: 22314694] |
| Journal of Animal and Veterinary Advances | A Soluble Antigen-Specific Factor from CD4+CD25+ T Cells of OVA Tolerant Mice Inducing OVA-Specific Peripheral Tolerance Independently in vivo [Medwell: 2011642650] |
| revue de medecine veterinaire | Increased circulating concentrations of PDGF-BB and TGF-β1 in canine generalised demodicosis [Revmedvet: Source] |
| Biomedical and Environmental Sciences | The Intervention Effect of Rosiglitozone in Ovarian Fibrosis of PCOS Rats [Besjournal: Source] |
| The Open Respiratory Medicine Journal | Biomarkers of Fibroproliferative Healing in Fibrosing Idiopathic Interstitial Pneumonias [PubMed: PMC3551240] |
| PLoS ONE | A Combinatorial Relative Mass Value Evaluation of Endogenous Bioactive Proteins in Three-Dimensional Cultured Nucleus Pulposus Cells of Herniated Intervertebral Discs: Identification of Potential Target Proteins for Gene Therapeutic Approaches [Plosone: Source] |
| J Physiol Pharmacol. | Fibrogenic response of hepatic stellate cells in ovarectomised rats exposed to ketogenic diet [Pubmed: 23568967] |
| international Journal of food and nutritional sciences | EVALUATION OF PHYSICO-CHEMICAL PROPERTIES OF COLOSTRUM SUPPLEMENTED DAHI [Ijfans: Source] |
| Journal of ethnopharmacology | Multitargeted protective effect of Abacopteris penangiana against carrageenan-induced chronic prostatitis in rats. [Pubmed: 24211397] |
| Int J Clin Exp Pathol | Development of a KLD-12 polypeptide/TGF-β1-tissue scaffold promoting the differentiation of esenchymal stem cell into nucleus pulposus-like cells for treatment of intervertebral disc degeneration [Ijcep:Source] |
| Am J Physiol Regul Integr Comp Physiol. | Prolactin anterior pituitary expression and circulating levels are reduced in obese and diabetic rats: Role of TGFβ and TNFα [Pubmed:25715833] |
| Exp Ther Med. | PAR2, IL4R, TGFβ and TNFα in bronchoalveolar lavage distinguishes extrinsic allergic alveolitis from sarcoidosis [Pubmed:Pmc4079423] |
| International Journal of Molecular Medicine | Effect of combined treatment with rosuvastatin and protein kinase Cβ2 inhibitor on angiogenesis following myocardial infarction in diabetic rats [Pubmed:25524396] |
| Indian J Pharmacol | Effect of coenzyme Q10 alone and its combination with metformin on streptozotocin-nicotinamide-induced diabetic nephropathy in rats [Pubmed:25538335] |
| Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) | Ameliorative potential of omega 3 fatty acids and HMG-CoA reductase inhibitors on experimentally-induced non-alcoholic steatohepatitis [Pubmed:25541279] |
| Anadolu Kardiyol Derg. | A novel association between TGFb1 and ADAMTS4 in coronary artery disease: A new potential mechanism in the progression of atherosclerosis and diabetes. [Pubmed:25592103] |
| Journal of Drug | Targeting Apoptosis, Advanced Glycation End Products and Transforming Growth Factor-β1 by Biguanides and Resveratrol to Ameliorate Experimentally-induced Diabetic Nephropathy [Pdf: Drugs] |
| Mol Med Rep | NIM811 downregulates transforming growth factor [PubMed: 26573209] |
| The Tohoku Journal of Experimental Medicine | Salvia Miltiorrhiza Bge.f.alba Ameliorates the Progression of Monocrotaline-Induced Pulmonary Hypertension by Protecting Endothelial Injury in Rats [PubMed: 26074502] |
| Oncol Rep | Therapeutic effects of bone marrow-derived mesenchymal stem cells on radiation-induced lung injury [PubMed: 26717975] |
| J Surg Res | Epigallocatechin-3-gallate reduces tubular cell apoptosis in mice with ureteral obstruction [PubMed: 25913488] |
| Histol Histopathol | Estrogen-deficient osteoporosis enhances the recruitment and activity of osteoclasts by breast cancer cells [PubMed: 26254457] |
| Clin Exp Pharmacol Physiol | Silymarin attenuates paraquat-induced lung injury via Nrf2-mediated pathway in vivo and in vitro [PubMed: 26173462] |
| Immunologic Research | Mesenchymal stromal cell-dependent reprogramming of Kupffer cells is mediated by TNF-α and PGE6 and is crucial for liver transplant tolerance [PubMed: 25982596] |
| Journal of Neuroscience | MSX3 Switches Microglia Polarization and Protects from Inflammation-Induced Demyelination [PubMed: 25904788] |
| J Reprod Immunol | The immunomodulating effect of seminal plasma on T cells [PubMed: 25799173] |
| Nutr Cancer | Camel Milk: Potential Utility as an Adjunctive Therapy to Peg-IFN/RBV in HCV-4 Infected Patients in Egypt [PubMed: 26492130] |
| Int J Clin Exp Med | Uighur medicine abnormal savda munzip (ASMq) suppresses expression of collagen and TGF-β1 with concomitant induce Smad7 in human hypertrophic scar … [PubMed: 26309506] |
| Int J Clin Exp Pathol | Development of a KLD-12 polypeptide/TGF-β1-tissue scaffold promoting the differentiation of mesenchymal stem cell into nucleus pulposus-like cells for treatment of intervertebral disc degeneration. [PubMed: 25972996] |
| International Immunopharmacology | Oxymatrine attenuates CCl 4-induced hepatic fibrosis via modulation of TLR4-dependent inflammatory and TGF-β1 signaling pathways [Pubmed:27179304] |
| Deletion Polymorphism and Chronic Obstructive Pulmonary Disease | ReCavia (Guinea pig )lation of Viral Infection-induced Airway Remodeling Cytokine Production by the TLR3-EGFR Signaling Pathway in Human Bronchial Epithelial Cells [Pubmed:27075970] |
| Tissue and Cell | Human umbilical cord blood-mesenchymal stem cells transplantation renovates the ovarian surface epithelium in a rat model of premature ovarian failure: Possible direct and indirect effects [Pubmed:27233913] |
| Cancer Medicine & Anti Cancer Drugs | Ameliorative Potential of Tamoxifen/Thymoquinone Combination in Patients with Breast Cancer: A Biochemical and Immunohistochemical Study [open-access:1000102] |
| Sleep Sciences | Th17 Cell Related Cytokine Profiles in Narcolepsy and Other Types of Excessive Daytime Sleepiness [article:15] |
| Tissue Cell. | Ameliorative potential of fluoxetine/raloxifene combination on experimentally induced breast cancer [Pubmed:26881735] |
| International Journal of Molecular Sciences | TGF-β and Physiological Root Resorption of Deciduous Teeth. [pubmed:28035998] |
| BMC Veterinary Research | Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis [pubmed:27553600] |
| immunology letters | Recombinant Mip-PilE-FlaA dominant epitopes vaccine candidate against Legionella pneumophila. [pubmed:28366526] |
| immunology letters | Gemcitabine treatment enhanced the anti-tumor effect of cytokine induced killer cells by depletion of CD4+CD25bri regulatory T cells. [pubmed:27867030] |
| Journal of Cardiovascular Electrophysiology | Effect of Cardiac Resynchronization Therapy on Myocardial Fibrosis and Relevant Cytokines in a Canine Model With Experimental Heart Failure. [pubmed:28127817] |
| Molecular Medicine Reports | The?protective?role?of?vitamin?D3?in a?murine?model?of?asthma?via?the?suppression?of TGF-β/Smad?signaling?and?activation?of the?Nrf2/HO-1?pathway. [pubmed:27484042] |
| International Immunopharmacology | Amelioration of bleomycin-induced lung fibrosis in rats by valproic acid and butyrate: Role of nuclear factor kappa-B, proinflammatory cytokines and oxidative stress [pubmed:27526269] |
| Cellular?Physiology and Biochemistry | Renal Denervation Attenuates Multi-Organ Fibrosis and Improves Vascular Remodeling in Rats with Transverse Aortic Constriction Induced Cardiomyopathy [pubmed:27889753] |
| Canadian Journal of Physiology and Pharmacology | The effect of midkine on growth factors and oxidative status in an experimental wound model in diabetic and healthy rats [pubmed:28177680] |
| PLoS One. | Differential frequency of CD8+ T cell subsets in multiple sclerosis patients with various clinical patterns [pubmed:27467597] |
| Therapeutics?and?Clinical?Risk?Management | Elevated?blood?plasma?levels?of?epinephrine,?norepinephrine,?tyrosine?hydroxylase, TGFβ1, and TNFα?associated?with?high-altitude?pulmonary?edema?in an Indian population. [pubmed:27540296] |
| Journal of Cancer Research and Treatment | Effect of Indole-3-carbinol and/or Metformin on Female Patients with Ulcerative Colitis (Premalignant Condition): Role of Oxidative Stress, Apoptosis and Proinflammatory Cytokines [jcrt:5] |
| Sci Rep | Follistatin like-1 aggravates silica-induced mouse lung injury [PMC5428474] |
| Ren Fail.? | Effect of concomitant administration of coenzyme Q10 with sitagliptin on experimentally induced diabetic nephropathy in rats. [pubmed:27841100] |
| Basic Clin Pharmacol Toxicol. | Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4+ T Helper 17 (Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling. [pubmed:28032440] |
| Acta Vet Hung. | Imbalance of intestinal immune function in piglets infected by porcine circovirus type 2 during the fetal period. [pubmed:28244338] |
| Gut Pathog. | Oral administration of Clostridium butyricum CGMCC0313‐1 reduces ovalbumin‐induced allergic airway inflammation in mice [pubmed:28250847] |
| Environmental Toxicology and Pharmacology | Ameliorative potential of linagliptin and/or calcipotriol on bleomycin-induced lung fibrosis: In vivo and in vitro study [pubmed:28192751] |
| PeerJ | Platelet-rich concentrate in serum free medium enhances osteogenic differentiation of bone marrow-derived human mesenchymal stromal cells [pubmed:27651984] |
| Biomedical and Environmental Sciences | Crystalline Silica Promotes Rat Fibrocyte Differentiation?in Vitro, and Fibrocytes Participate in Silicosis?in Vivo [pubmed:29081339] |
| Toxicology and Applied Pharmacology | Sildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1) [pubmed:28974454] |
| Oral Diseases | Glucosamine oral administration as an adjunct to hyaluronic acid injection in treating temporomandibular joint osteoarthritis [pubmed:28862770] |
| Biomedicine & Pharmacotherapy | Cytokine production in vitro and in rat model of colitis in response to Lactobacillus plantarum LS/07 [pubmed:28830068] |
| Research in Veterinary Science | The effect of feed supplementation with effective microorganisms(EM) on pro- and anti-inflammatory cytokine concentrations in pigs [pubmed:28549299] |
| Journal of Materials Chemistry B | Extracellular Matrix Powder from Cultured Cartilage-Like Tissue as Cell Carriers for Cartilage Repair [DOI:10.1039/C7TB00640C] |
| National Natural Scientific | Role of Gut-Derived Endotoxin on Type I Collagen Production in the Rat Pancreas after Chronic Alcohol Exposure [pubmed:29121396] |
| Basic & Clinical Pharmacology & Toxicology | Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4 + T Helper 17(Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 Signalling [doi:10.1111] |
| Experiental And Therapeutic Medicine | Plasma proteins as potential targets of abnormal Savda syndrome in asthma patients treated with unique Uighur prescription [pubmed:28672924] |
| Oncotarget. | Tumor-associated macrophages promote tumor metastasis via the TGF-β/SOX9 axis in non-small cell lung cancer [pubmed:29245941] |
| International Journal of Chemical Studies | Studies on quality attributes of skimmed colostrum powder [P-ISSN: 2349–8528] |
| Scientific RepoRts | Follistatin like-1 aggravates silicainduced mouse lung injury [pubmed:28341862] |
| Evidence-Based Complementary and Alternative Medicine | Cardioprotection against Heart Failure by Shenfu Injection via TGF-β/Smads Signaling Pathway [pubmed:28698735] |
| Molecular Medicine Reports | Pigment epithelium?derived factor protects human glomerular mesangial cells from diabetes via NOXO1?iNOS suppression [10.3892/mmr.2017.7563] |
| ARTIFICIAL?CELLS?NANOMEDICINE AND BIOTECHNOLOGY? | Dexamethasone reduces serum level of IL-17 in Bleomycin-A5-induced rats model of pulmonary fibrosis [pubmed:28608724] |
| Cell Physiol Biochem | Exendin-4 Induces Bone Marrow Stromal Cells Migration Through Bone Marrow-Derived Macrophages Polarization via PKA-STAT3 Signaling Pathway [pubmed:29216639] |
| Chemico-biological Interactions | The promising effect of linagliptin and/or indole-3-carbinol on experimentally-induced polycystic ovarian syndrome. [pubmed:28619389] |
| PLoS One | Protective effect of aplysin on liver tissue and the gut microbiota in alcohol-fed rats [pubmed:28622357] |
| Evidence-based complementary and alternative medicine | Qiliqiangxin Enhances Cardiac Glucose Metabolism and Improves Diastolic Function in Spontaneously Hypertensive Rats [pubmed:28706558] |
| Molecular and Cellular Neuroscience | TGF-β1 enhances phagocytic removal of neuron debris and neuronal survival by olfactory ensheathing cells via integrin/MFG-E8 signaling pathway [10.1016/j.mcn.2017.08.006] |
| Journal of?Thoracic?Oncology | Systemic and Tumor Th1 and Th2 Inflammatory Profile and Macrophages in Lung Cancer: Influence of Underlying Chronic Respiratory Disease. [pubmed:27793775] |
| Journal?of?Controlled?Release | Nose-to-brain delivery of insulin enhanced by a nanogel carrier [Pubmed:29196041] |
| Journal of?Cellular?And Molecular?Medicine? | Lipopolysaccharide enhances TGF‐β1 signalling pathway and rat pancreatic fibrosis [Pubmed:29424488] |
| International Journal of Biochemistry &?Cell?Biology | Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling [Pubmed:29940125] |
| Physiology &?Behavior? | Linagliptin potentiates the effect of l-dopa on the behavioural, biochemical and immunohistochemical changes in experimentally-induced Parkinsonism: Role of toll?… [Pubmed:29410018] |
| Journal of Molecular Neuroscience | A Novel scFv Anti-Aβ Antibody Reduces Pathological Impairments in APP/PS1 Transgenic Mice via Modulation of Inflammatory Cytokines and Aβ-related Enzymes [Pubmed:30062438] |
| Oncotarget | Nucleoside reverse transcriptase inhibitor-induced rat oocyte dysfunction and low fertility mediated by autophagy [Pubmed:29423092] |
| Oncotarget | Hypoxia-inducible factor-1α activates transforming growth factor-β1/Smad signaling and increases collagen deposition in dermal fibroblasts [Pubmed:29423039] |
| Communications Biology | Activated hepatic stellate cells promote epithelial-to-mesenchymal transition in hepatocellular carcinoma through transglutaminase 2-induced pseudohypoxia [] |
| Bulletin?of Experimental?Biology?and?Medicine | Expression of Hif-1α, Nf-κb, and Vegf Genes in the Liver and Blood Serum Levels of HIF-1α, Erythropoietin, VEGF, TGF-β, 8-Isoprostane, and Corticosterone in Wistar Rats with High and Low Resistance to Hypoxia. Corticosterone in?… [Pubmed: 30353332] |
| Phytomedicine | Mechanistic insights to the cardioprotective effect of Blueberry Nutraceutical Extract in Isoprenaline-Induced Cardiac Hypertrophy [] |
| Veterinary?Immunology?and?Immunopathology | Evaluation of T regulatory lymphocytes and serum concentration of selected cytokines in dogs with perianal tumors [] |
| Experimental?and Therapeutic Medicine | Rhynchophylline attenuates allergic bronchial asthma by inhibiting transforming growth factor?β1?mediated Smad and mitogen?activated protein kinase signaling?… [] |
| Biology?of?Reproduction | Recombinant adiponectin alleviates abortion in mice by regulating Th17/Treg imbalance via p38MAPK-STAT5 pathway [Pubmed: 30496353] |
| International Journal of Peptide Research and Therapeutics | ANP/NPRA Inhibits Epithelial-Mesenchymal Transition of Airway by Targeting Smad3 in Asthma [] |
| Journal of?Neuroinflammation | Anti-inflammatory and cognitive effects of interferon-β1a (IFNβ1a) in a rat model of Alzheimer's disease [Pubmed: 30777084] |
| Biochimie | Periostin contributes to renal and cardiac dysfunction in rats with chronic kidney disease: reduction of PPARα [Pubmed: 30890453] |
| Molecular?Medicine?Reports | Astaxanthin ameliorates renal interstitial fibrosis and peritubular capillary rarefaction in unilateral ureteral obstruction [Pubmed: 30816496] |
| International Journal of?Nanomedicine | Improving the anti-keloid outcomes through liposomes loading paclitaxel–cholesterol complexes [Pubmed: 30863067] |
| Behavioural Brain Research | THE ROLE OF ANTI-INFLAMMATORY CYTOKINES IN MEMORY PROCESSING IN A HEALTHY BRAIN [] |
| International Journal of Ophthalmology | A novel xeno-free culture system for human retinal pigment epithelium cells [Pubmed: 31024807] |
| Open Access Macedonian Journal of Medical Sciences | Low Degree Hyaluronic Acid Crosslinking Inducing the Release of TGF-Β1 in Conditioned Medium of Wharton's Jelly-Derived Stem Cells [] |
| 中國(guó)免疫學(xué)雜志 | TRAF-6 調(diào)控TGF-β1-Smad2/Smad3 信號(hào)通路在Graves 病免疫發(fā)病機(jī)制中的作用 [] |
| Food & Function | Network pharmacology oriented study reveals inflammatory state-dependent dietary supplement hepatotoxicity responses in normal and diseased rats [Pubmed: 31140472] |
| Annals of clinical and laboratory science | CD19+ CD24hiCD38hi Regulatory B cells Involved in Hepatic Alveolar Hydatid Infection in Humans [Pubmed: 31308033] |
| Life sciences | Pioglitazone attenuates kidney fibrosis via miR-21-5p modulation [Pubmed: 31254585] |
| Acta Histochemica | Hyperoside protects against heart failure-induced liver fibrosis in rats [Pubmed: 31353051] |
| Cardiology | Circulating Connective Tissue Growth Factor Is Associated with Diastolic Dysfunction in Patients with Diastolic Heart Failure [Pubmed: 31466059] |
| Scientific Reports | Anti-inflammatory and antioxidant effects of muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus [Pubmed: 31578381] |
| toxicology and applied pharmacology | miR-181b-5p inhibits endothelial-mesenchymal transition in monocrotaline-induced pulmonary arterial hypertension by targeting endocan and TGFBR1 [Pubmed: 31734320] |
| Experimental Cell Research | CD4+ CD25+ Tregs as dependent factor in the course of bleomycin-induced pulmonary fibrosis in mice [Pubmed: 31678213] |
| Prostaglandins & other Lipid Mediators | Lipoxin A4 inhibited the activation of Hepatic Stellate Cells-T6 cells by modulating profibrotic cytokines and NF-κB signaling pathway [Pubmed: 31698141] |
| International Journal of Rheumatic Diseases | Effects of thalidomide on Th17, Treg cells and TGF‐β1/Smad3 pathway in a mouse model of systemic sclerosis [Pubmed: 31840939] |
| Pigment Cell & Melanoma Research | Altered expression of nuclear factor of activated T cells, Forkhead Box P3 and immune suppressive genes in regulatory T cells of generalized vitiligo patients [Pubmed: 31917889] |
| Cell Communication and Signaling | Rapamycin promotes endothelial–mesenchymal transition during stress-induced premature senescence through the activation of autophagy [Pubmed: 32164764] |
| Biomed Pharmacother | Soufeng Yuchuan decoction mitigates the ovalbumin-induced lung damage in a rat model of asthma [Pubmed: 32036215] |
| Biochemical and Biophysical Research Communications | Isorhynchophylline exerts anti-asthma effects in mice by inhibiting the proliferation of airway smooth muscle cells: The involvement of miR-200a-mediated FOXC1/NF?… [Pubmed: 31733831] |
| INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | Vitamin D Attenuates Loss of Endothelial Biomarker Expression in Cardio-Endothelial Cells [Pubmed: 32235811] |
| Journal of Oral Biology and Craniofacial Research | Levels of TGF-β1 in peri-miniscrew implant crevicular fluid [Pubmed: 32211284] |
| Acta Histochem | Paeoniflorin accelerates foot wound healing in diabetic rats though activating the Nrf2 pathway [Pubmed: 33166863] |
| EUROPEAN JOURNAL OF PHARMACOLOGY | The anti-asthmatic potential of flavonol kaempferol in an experimental model of allergic airway inflammation [Pubmed: 33122672] |
| Journal of Cosmetic Dermatology | Examination of androgenetic alopecia with serum biomarkers [Pubmed: 32969583] |
| MOLECULAR AND CELLULAR BIOCHEMISTRY | Soluble recombinant human thrombomodulin suppresses inflammation-induced gastrointestinal tumor growth in a murine peritonitis model [Pubmed: 32767229] |
| CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | Hepatoprotective effect of Linagliptin against liver fibrosis induced by carbon tetrachloride in mice [Pubmed: 32726558] |
| EXPERIMENTAL DERMATOLOGY | Decreased suppression of CD8+ and CD4+ T cells by peripheral Regulatory T cells in Generalized Vitiligo due to reduced NFATC1 and FOXP3 proteins [Pubmed: 32682346] |
| Scientific Reports | Erlotinib can halt adenine induced nephrotoxicity in mice through modulating ERK1/2, STAT3, p53 and apoptotic pathways [Pubmed: 32661331] |
| international journal of biological macromolecules | Chlorella vulgaris α-L-arabino-α-L-rhamno-α, β-D-galactan structure and mechanisms of its anti-inflammatory and anti-remodelling effects [Pubmed: 32565301] |
| Exp Cell Res | Exosomal miR-532–5p from bone marrow mesenchymal stem cells reduce intervertebral disc degeneration by targeting RASSF5 [Pubmed: 32464126] |
| JOURNAL OF IMMUNOLOGY RESEARCH | The Sufficient Immunoregulatory Effect of Autologous Bone Marrow-Derived Mesenchymal Stem Cell Transplantation on Regulatory T Cells in Patients with … [Pubmed: 32411794] |
| Frontiers in Pharmacology | M10, a Myricetin-3-ObD-Lactose Sodium Salt, Prevents Ulcerative Colitis Through Inhibiting Necroptosis in Mice [Pubmed: 33041798] |
| Food & Function | Nicotinamide riboside alleviates alcohol-induced depression-like behaviours in C57BL/6J mice by altering the intestinal microbiota associated with microglial?… [] |
| Effect of metformin and indole-3-carbinol on a rat model of Parkinson's disease induced by 6-hydroxydopamine [] | |
| Research square | Vitamin D Status in Dupuytren's Disease: Association with Clinical Status and Vitamin D Receptor Expression [] |
| Phytomedicine | Menthacarin attenuates experimental colitis [] |
| Immunomodulatory effects of sCD83 via induction of TGF-β1 and IDO: an in vitro and rat orthotopic liver transplantation study [] | |
| BMC Complement Med Ther | Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma [33413331] |
| Life Sci | Celecoxib ameliorates liver cirrhosis via reducing inflammation and oxidative stress along spleen-liver axis in rats [33577848] |
| CLINICAL SCIENCE | Berberine accelerated wound healing by restoring TrxR1/JNK in diabetes [33491733] |
| Bioact Mater | New design to remove leukocytes from platelet-rich plasma (PRP) based on cell dimension rather than density [33842739] |
| Acta Biomater | Highly interconnected inverse opal extracellular matrix scaffolds enhance stem cell therapy in limb ischemia [33878473] |
| Mol Cell Biochem | Human umbilical cord-derived mesenchymal stem cells and their chondroprogenitor derivatives reduced pain and inflammation signaling and promote regeneration in??- [33864569] |
| Cell Death & Disease | Sodium/glucose cotransporter 1-dependent metabolic alterations induce tamoxifen resistance in breast cancer by promoting macrophage M2 polarization [34006822] |
| PLoS One | Beneficial impact of cathelicidin on hypersensitivity pneumonitis treatment?aIn vivo studies [33999928] |
| Vascular pharmacology | Nectin-4 promotes lymphangiogenesis and lymphatic metastasis in breast cancer by regulating CXCR4-LYVE1 axis [33945869] |
| Equine Vet J | Limited added value of negative pressure wound therapy compared to calcium alginate dressings for second intention healing in a non?\contaminated and??- [34115409] |
| Stem Cells International | The Paracrine Effect of Adipose-Derived Stem Cells Orchestrates Competition between Different Damaged Dermal Fibroblasts to Repair UVB-Induced Skin??- [33381190] |
| Journal of Pharmacy and Pharmacology | Pharmacodynamic evaluation of dihydroxyflavone derivate chrysin in a guinea pig model of allergic asthma [33793800] |
| Bull. Egypt. Soc. Physiol. Sci. | Flaxseed Oil Supplementation Afford Comparable Therapeutic effect to Metformin in Bleomycin Induced Pulmonary Fibrosis Rat model [] |
| D￡?ˉ | Role of Angiotensin II and Renal Nerves on TGF-b/SmadPathway in Diabetic Nephropathy Rat Model [] |
| Bioactive Materials | Calcium phosphate-based materials regulate osteoclast-mediated osseointegration [] |
| Mediators of Inflammation | Sparstolonin B Exerts Therapeutic Effects on Collagen-Induced Arthritis by Inhibiting the NLRP3 Inflammasome and Reducing the Activity of |á1, 3 ?- [] |
| Manuscript title Microparticles Containing MiR-625-5p In Coronary Artery Reduce Myocardial Fibrosis After Myocardial Infarction [] | |
| Andrology | X‐ray micro‐computed tomography in the assessment of penile cavernous fibrosis in a rabbit castration model [34236146] |
| Aging | Yiqi Jiemin decoction alleviates allergic rhinitis in a guinea pig model by suppressing inflammation, restoring Th1/Th2 balance, and improving cellular?… [34315133] |
| Tissue Eng Regen Med | Effect of Leukocyte-Platelet Rich Fibrin (L-PRF) on Tissue Regeneration and Proliferation of Human Gingival Fibroblast Cells Cultured Using a Modified Method [34339025] |
| Am J Transl Res | Wuling San and Xiao Chaihu Decoction affect airway inflammatory response and airway smooth muscle cell proliferation in mice with allergic asthma via miR?… [34786062] |
| Biomacromolecules | In Situ Forming Cellulose Nanofibril-Reinforced Hyaluronic Acid Hydrogel for Cartilage Regeneration [34723499] |
| Brain Sci | Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial?… [34942919] |
| Biomedicines | Exploring Epithelial–Mesenchymal Transition Signals in Endometriosis Diagnosis and In Vitro Fertilization Outcomes [34829910] |
| J Inflamm Res | Clenbuterol, a Selective β2-Adrenergic Receptor Agonist, Inhibits or Limits Post-Stroke Pneumonia, but Increases Infarct Volume in MCAO Mice [Pubmed:35058704] |
| Cancer Commun (Lond) | Anti‐PD‐L1/TGF‐βR fusion protein (SHR‐1701) overcomes disrupted lymphocyte recovery‐induced resistance to PD‐1/PD‐L1 inhibitors in lung cancer [Pubmed:34981670] |
| Polymers (Basel) | 3D Printed Scaffold Based on Type I Collagen/PLGA_TGF-β1 Nanoparticles Mimicking the Growth Factor Footprint of Human Bone Tissue [Pubmed:35267680] |
| Biomed Pharmacother | Jiangu granule ameliorated OVX rats bone loss by modulating gut microbiota-SCFAs-Treg/Th17 axis [Pubmed:35453007] |
| Biomed Pharmacother | Huangbai liniment and berberine promoted wound healing in high-fat diet/Streptozotocin-induced diabetic rats [Pubmed:35430394] |
| Antioxidants | Bio-Evaluation of the Wound Healing Activity of Artemisia judaica L. as Part of the Plant's Use in Traditional Medicine; Phytochemical, Antioxidant, Anti-Inflammatory?… [Pubmed:35204215] |
| Frontiers in Molecular Neuroscience | Red Nucleus Interleukin-6 Evokes Tactile Allodynia in Male Rats Through Modulating Spinal Pro-inflammatory and Anti-inflammatory Cytokines [Pubmed:35465093] |
| Vaccines | Age-Dependent Dynamics of Maternally Derived Antibodies (MDAs) and Understanding MDA-Mediated Immune Tolerance in Foot-and-Mouth Disease-Vaccinated?… [Pubmed:35632433] |
| Biomaterials Advances | Human adipose-derived stem cell-loaded small intestinal submucosa as a bioactive wound dressing for the treatment of diabetic wounds in rats [] |
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